Endocrine Abstracts

Objective: Generously supported by IPSEN)-->Abscesses in pituitary adenomas are rare. Continuous progression and haematogenous spread of infections are considered the main pathogenic mechanisms. A standard therapeutic regimen does not exist.Methods: We report on the case of a 56-year-old male who had been treated with cabergoline for a macroprolactinoma for 4.5 years. The patient presented to our emergency room...

Objective: 8-Prenylnaringenin (8-PN) is a phytoestrogen discovered in hops. GH3 pituitary adenoma cells of the rat show a variety of responses to phytoestrogens in vitro. This in vitro study aims to analyze changes in hormone expression in GH3 cells treated with 8-PN.Methods: GH3 cells were incubated with 0.5–50 μM 8-PN for 4 h. Medium and ethanol served as controls. Changes in expression of growth hormone (GH) and prolactin (...